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Published on March 23, 2022

From diabetes, to high blood pressure, and more… Magnesium and vitamin D work together synergistically, in such a way that the interaction of both is greater than the sum of their individual effects

Key Points

  • Vitamin D and magnesium each have their own effects on health, including lowering high blood pressure. However, a new study shows that the combination of higher vitamin D levels and higher magnesium intake has an even stronger effect on lowering blood pressure than either alone.
  • Higher vitamin D levels were associated with a decreased incidence of type 2 diabetes, and the significance of the effect was greater among those who got more magnesium
  • Studies looking at the combined effect of vitamin D and magnesium have had outcomes such as improved ADHD symptoms, reduced severity of COVID-19, reduced risk of anemia, and improved cognition

Magnesium is an important co-nutrient for vitamin D, and is involved in the biosynthesis, transport, and activation of vitamin D. Studies have shown that poor magnesium status potentially impairs vitamin D metabolism enough to limit the parathyroid hormone (PTH) response, which increases the activation of vitamin D to then increase calcium absorption.

An existing magnesium deficiency may also result in a vitamin D level that does not increase as much as expected in response to vitamin D supplementation. As illustrated by Deng et al., without sufficient magnesium, the amount of vitamin D that can be metabolized and used by the body is limited and may result in a lack of conversion of vitamin D into its other active forms.

Higher Magnesium Intake Strengthens Effect of Vitamin D on Lowering Blood Pressure

It is known that vitamin D and magnesium each have their own effects on health, including lowering high blood pressure. However, a new study shows that the combination of higher vitamin D levels and higher magnesium intake has an even stronger effect on lowering blood pressure than either alone.

The study by Huang et al. looked at how magnesium intake affected the association between vitamin D and blood pressure among 8,799 adults ages 20 years or older. The data used was from the National Health and Nutrition Examination Survey (NHANES) from 2007 through 2014. Comparisons were made between vitamin D and systolic blood pressure (SBP) and vitamin D and diastolic blood pressure (DBP) with either low magnesium intake (less than 299 mg per day) or high intake (at least 299 mg per day).

This study not only confirmed vitamin D’s relationship to SBP, where higher vitamin D levels were associated with lower SBP, it also showed that the relationship between vitamin D and systolic blood pressure was stronger among the high magnesium intake group compared to the low magnesium intake group.

As the authors state,

“it was found that dietary magnesium intake and vitamin D had an interactive effect on reducing SBP in most of the models, which indicates that the interaction of high serum vitamin D and high intake of magnesium is greater than the sum of the individual effects.”

Magnesium Intake Also Affects Association between Vitamin D and Risk of Type 2 Diabetes

Another study by Huang et al. found that magnesium intake affected the association between vitamin D level and the incidence of type 2 diabetes, where the distribution of vitamin D levels between participants with or without type 2 diabetes was not significantly different in the low magnesium intake group, but was in the high magnesium intake group.

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In the group with high magnesium intake, there was a 35% significantly decreased risk of type 2 diabetes among the participants with vitamin D sufficiency compared to those with vitamin D deficiency, compared to the group with low magnesium intake, which only had a 12% decreased risk among those with vitamin D sufficiency, and the finding was not significant.

In other words, higher vitamin D levels were associated with a decreased incidence of type 2 diabetes, and the significance of the effect was greater among those who got more magnesium.

Other Outcomes Associated with the Combination of Vitamin D and Magnesium

Studies looking at the combined effect of vitamin D and magnesium have had outcomes such as improved ADHD symptoms, reduced severity of COVID-19, reduced risk of anemia, and improved cognition.

Make Sure You Are Getting Enough of Both Vitamin D, and Magnesium!

Having and maintaining healthy vitamin D levels and other nutrient levels can help improve your health now and for your future. Choose which additional nutrients to measure, such as your omega-3s and essential minerals including magnesium and zinc, by creating your custom home test kit today. Take steps to improve the status of each of these measurements to benefit your overall health. With measurement you can then determine how much is needed and steps to achieve your goals.  You can also track your own intakes, symptoms and results to see what works best for YOU.

Enroll in D*action and Test Your Levels Today!

What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?

Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.

STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.

STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).

STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.

STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.

STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.

STEP 6 – Adjust, Repeat…

Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.

NEWS ALERT

The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.

These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.

Review the Latest Nutrient Research for COVID-19

GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:

  • Vitamin D
  • Omega-3 Index
  • Essential elements magnesium, selenium, and zinc
  • hsCRP

Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!

Please let us know if you're interested in helping sponsor this project.

CLICK HERE for updates and new information about the project.

Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

Click Here to Access the Test Page

How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called

For each specific supplement, you can track what days you take it, how much, and many other details.  This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!