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Gestational diabetes, which causes high blood sugar and can lead to fetal and maternal complications, affects 5% of pregnancies worldwide. In women with gestational diabetes, extra calories and increased weight induce inflammatory pathways which could lead to insulin resistance. Obesity is one underlying factor that may contribute to gestational diabetes through the increased risk of oxidative stress (an imbalance between free radicals and antioxidants in the body).

Earlier this year (March 2019), results were published from a clinical trial assessing the effect of co-supplementation with magnesium, zinc, calcium, and vitamin D, all of which have anti-inflammatory and antioxidant properties, on pregnancy outcomes among women with gestational diabetes. In this trial, 60 women with gestational diabetes were assigned to either co-supplementation (200 mg magnesium, 8 mg zinc, 800 mg calcium, and 400 IU vitamin D per day) or placebo for 6 weeks.

What were the findings of the study?

The researchers found that those assigned to co-supplementation had a significant reduction in biomarkers for inflammation (P=0.01) and oxidative stress (P=0.003) compared to those in the placebo group. Also, the co-supplementation group had a significant increase in total antioxidant capacity, a measure of antioxidant status where higher levels indicate lower oxidative stress, compared to the placebo group (P=0.01).

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Additionally, infants of mother’s with gestational diabetes are at risk for macrosomia, which describes a newborn who is significantly larger than average. Macrosomia can lead to difficulties with delivery, low blood sugar levels in the newborn, and increased risk of obesity and metabolic syndrome in childhood. In this trial, women in the co-supplementation group had smaller newborns compared to women in the placebo group (3090 vs. 3346 grams, P=0.05) and had a lower rate of macrosomia (3.3% vs. 16.7%, P=0.08).

These findings suggest that providing women with gestational diabetes with magnesium, zinc, calcium, and vitamin D supplements could improve biomarkers for inflammation and oxidative stress and possibly reduce macrosomia. Of note, the vitamin D dose in this trial was very small and women in the co-supplementation group only achieved a vitamin D level of 19 ng/ml. It’s likely that women and infants in the co-supplementation group would have experienced even better results had the dose been much higher.

Do you have existing chronic inflammation?

Chronic inflammation can lead to chronic disease, and symptoms such as pain, chronic fatigue, depression and anxiety. The presence of inflammation can indicate the need for dietary changes and the improvement of nutrient levels. GrassrootsHealth offers an Inflammation Panel to test your hsCRP, vitamin D, omega-3 and HbA1c levels, to give you a better idea of your current state of inflammation and how to address it. Find out your levels today! Log on to the shop (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

Click Here to Access the Shop Page

How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created an online tracking system called myData-myAnswers. For each specific supplement, you can track what days you take it, how much, and many other details. This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!

Important Message

NEWS ALERT: States, Governments Acknowledge the Need for Vitamin D to Build the Immune System; Vitamin D*action has achieved a major milestone of ‘Moving Research into PRACTICE’!

EVERYONE needs to know about the benefits of vitamin D... We need your help to do this. Donating $25.00 today will positively affect millions of lives!

We will take this opportunity to use our extensive network to get pertinent information on vitamin D to the new US COVID Panel as well as local and state government representatives around the world.

Donate $25 today to help support this outreach effort (and, let us know if your employer could match the donations made by individuals from now until January 1, 2021!). You can also "text-to-give" by simply texting Daction to 44321.

Donations made through GiveLively are received in full by GrassrootsHealth.

What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?

Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.

STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.

STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).

STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.

STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.

STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.

STEP 6 – Adjust, Repeat…

Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.

NEWS ALERT

The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.

These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.

Review the Latest Nutrient Research for COVID-19

GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:

  • Vitamin D
  • Omega-3 Index
  • Essential elements magnesium, selenium, and zinc
  • hsCRP

Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!

Please let us know if you're interested in helping sponsor this project.

CLICK HERE for updates and new information about the project.

Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

Click Here to Access the Test Page

How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called

For each specific supplement, you can track what days you take it, how much, and many other details.  This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!