Published on August 13, 2019

Did you know that magnesium supplementation has some of the same effects on cholesterol as statin drugs? Today we will highlight key insights from a paper by Andrea Rosanoff and Mildred Seelig which compare the mechanisms and effects of magnesium and statin drugs.

High LDL cholesterol levels, low HDL cholesterol levels, and high triglyceride levels are associated with increased cardiovascular disease risk. In the 1970s and 80s, statin drugs were developed to lower LDL cholesterol levels and prevent cardiovascular disease. Statins work by blocking an enzyme (HMG CoA Reductase) that your body uses to make cholesterol.

Similarly, when there is sufficient magnesium in the body, it works to inactivate this same enzyme though natural control mechanisms. Magnesium is also necessary for another enzyme (LCAT) which lowers LDL and triglyceride levels and raises HDL levels. Further, magnesium activates other enzymes involved in lipid production, such as the conversion of omega-3 and omega-6 into prostaglandins which are important for cardiovascular and general health.

Additionally, both statin drugs and magnesium prevent clotting and atherosclerotic plaques and reduce inflammation. While statins can raise liver enzymes and cause myopathy, a muscle disease resulting in muscular weakness, and cause other side effects, magnesium can protect against myopathy and only has mild gastrointestinal side effects for some. The cost difference is also a differing factor, with statin drugs costing at least $100/month (but may be covered by insurance) compared to magnesium supplements which are less than $20/month.

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While statin drugs lower LDL levels more sharply than magnesium, magnesium works through the same pathway to lower LDL levels and more reliably lowers triglycerides and raises HDL, which are also associated with cardiovascular disease. Further, magnesium has similar effects on clotting, plaque formation, and inflammation without the adverse effects and cost associated with statin drugs.

Are you getting enough magnesium?

Make sure your magnesium levels are not too low. Getting enough magnesium has been linked to a decreased risk of cardiovascular, mental-emotional, bone health and more. Find out your levels today! Log on to the shop (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

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How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created an online tracking system called myData-myAnswers. For each specific supplement, you can track what days you take it, how much, and many other details. This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!

How Can You Use this Information for YOUR Health?

Having and maintaining healthy vitamin D and other nutrient levels can help improve your health now and for your future. Measuring is the only way to make sure you are getting enough!

STEP 1 Order your at-home blood spot test kit to measure vitamin D and other nutrients of concern to you, such as omega-3s, magnesium, essential and toxic elements (zinc, copper, selenium, lead, cadmium, mercury); include hsCRP as a marker of inflammation or HbA1c for blood sugar health

STEP 2 Answer the online questionnaire as part of the GrassrootsHealth study

STEP 3 Using our educational materials and tools (such as our dose calculators), assess your results to determine if you are in your desired target range or if actions should be taken to get there

STEP 4 After 3-6 months of implementing your changes, re-test to see if you have achieved your target level(s)

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