The “Barker Hypothesis,” also known as the “The Fetal Origins Hypothesis,” theorizes that certain adult-onset diseases originate from nutritional deficiencies during the perinatal period (during pregnancy or in early infancy). These damages are irreversible beyond certain critical points in development, even following full nutrient repletion.
In the publication “Is Vitamin D Inadequacy in Early Life an Instance of the ‘Barker Hypothesis’?“, Dr. Robert Heaney evaluates prenatal vitamin D deficiency as part of the Barker hypothesis, and correlates it to diseases with an onset later in life such as Multiple Sclerosis (MS), Type 1 Diabetes, Preeclampsia, Schizophrenia, and other cognitive function and learning disabilities.
Dr. Heaney refers to a study by Willer et al. of more than 44,000 adult patients with MS from Canada, the UK, Denmark and Sweden. The chart below presents the ratio of the observed to expected cases of MS by birth month.
Note: If there were no seasonal variation, observed cases would be spread evenly across the year, with each month accounting for approximately 1/12 of the annual total. What we see, however, is a noticeably higher risk of MS observed in individuals born in May (following a winter pregnancy), and a lower risk in individuals born in November (following a summer pregnancy).
Dr. Heaney closes his review with an emphasis that the prenatal vitamin D serum level needed for protection from delayed outcomes such as those described above are physiological levels (40-60 ng/ml) and not pharmacological. Thus, ensuring a vitamin D status of 40-60 ng/ml during pregnancy is a safe protective measure to prevent later-onset diseases, such as MS, originating in a vitamin D deficient perinatal environment.
Read the review published here.
How can I track my vitamin D levels?
To help you track your vitamin D and other nutrient levels, GrassrootsHealth has created an online tracking system called myData-myAnswers. This will help you know how your supplementation and intake may be affecting you and impacting your health. Check it out today!
What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.
STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.
STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).
STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.
STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.
STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.
STEP 6 – Adjust, Repeat…
Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.
The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.
These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.
GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:
- Vitamin D
- Omega-3 Index
- Essential elements magnesium, selenium, and zinc
Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!
Please let us know if you're interested in helping sponsor this project.
Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.
Make sure you track your results before and after, about every 6 months!
How can I track my nutrient intake and levels over time?
To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called
For each specific supplement, you can track what days you take it, how much, and many other details. This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!