Published on April 21, 2021
First RCT of omega-3 supplementation for critically ill COVID-19 patients shows significant increase in one-month survival rates among those receiving omega-3s compared to control
Omega-3 fatty acids have been shown to be important regulators of inflammation and immune function in chronic disease, with actions such as increasing cell membrane stability, blocking hyper-inflammatory responses, and improving the immune response. We have previously discussed the anti-inflammatory, immune-modulating, and potential antiviral roles of omega-3s and how they may contribute to the prevention of and response to COVID-19 disease, and recently reviewed a pilot study showing a 75% lower risk of death due to COVID-19 among patients with a higher Omega-3 Index.
First Published Randomized Clinical Trial on Omega-3 Supplementation among COVID-19 ICU Patients
A double-blind, randomized controlled clinical trial by Doaei et al. looked at the effects of omega-3 fatty acid supplementation on inflammatory and biochemical markers among COVID-19 patients in the intensive care unit (ICU). The study included 128 critically ill patients between the ages of 35 and 85 years old; 42 of the patients received supplementation and 86 did not. Blood samples were collected at baseline and after 14 days of intervention, and included markers known to be representative of immune, respiratory, and renal function.
What did the study find?
As shown in the chart above, when looking at the survival rate among both groups, those who were in the omega-3 supplement group had a significantly higher chance of survival at one month; a 21% chance of surviving for those treated with omega-3 supplements compared to only 3% survival for those not receiving omega-3s (p=0.005). That is a 7 times higher chance of surviving for those receiving omega-3 fatty acid supplementation.
Other statistically significant improvements among the supplementation group included higher levels of respiratory function, including arterial pH, bicarbonate (HCO3), and Be (related to better endothelial function and microcirculation), as well as better kidney function including lower levels of BUN, Creatinine, and potassium (K) compared to the control group. These findings indicate that omega-3 supplementation may have protective effects on kidney and circulatory functions for patients with severe COVID-19, helping to prevent death due to renal impairment and acidosis.
Check Your Levels of Omega-3s and Vitamin D
Vitamin D has also been shown to greatly reduce the risk of COVID-19 severity and death, as outlined in some of the studies mentioned below.
With almost 90% of the general population having vitamin D levels below the recommended 40-60 ng/ml (100-150 nmol/L), it is obvious that most people need more vitamin D. While most of us cannot achieve a vitamin D level of 40-60 ng/ml from sun alone, either due to our lifestyle, where we live, or other circumstances, we can certainly reach those levels with the right amount of supplementation.
By joining the GrassrootsHealth projects, you are not only contributing valuable information to our study, but you are also gaining knowledge about how you could improve your own health through measuring and tracking your nutrient status, and educating yourself on how to improve it. Do you know what your status of vitamin D, omega-3s, and other essential nutrients is? Could your levels be improved? Test now to find out!
We now have a NEW GIFTING SERVICE that allows you to quickly send ‘Gift Cards’ to friends, family and coworkers who you consider might need immediate access to testing, and to Claim the Joy of Your Health TODAY. Give the gift today!
What does the Research Say about Vitamin D & COVID-19?
It’s TIME to start saving lives! If you can help PREVENT the majority of the death, it’s time! What’s it costing you/us not to take action NOW?
There is much published research that supports a clear link between vitamin D and COVID-19 showing that higher vitamin D levels are related to:
Be sure to educate yourself on the benefits and importance of vitamin D for immune health, and take steps to ensure you and your loved ones are getting enough.
You can review all of the COVID-19 and immune health information we have shared on this page.
What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?
Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.
STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.
STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).
STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.
STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.
STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.
STEP 6 – Adjust, Repeat…
Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.
The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.
These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.
GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:
- Vitamin D
- Omega-3 Index
- Essential elements magnesium, selenium, and zinc
Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!
Please let us know if you're interested in helping sponsor this project.
Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.
Make sure you track your results before and after, about every 6 months!
How can I track my nutrient intake and levels over time?
To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called
For each specific supplement, you can track what days you take it, how much, and many other details. This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!