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Published on April 5, 2022

Study finds increasing zinc levels among participants diagnosed with anxiety was associated with a 31% decrease in anxiety rating

Key Points

  • Zinc has protective effects against DNA damage and oxidative stress, which have also been correlated with anxiety; prolonged deficiency of zinc has been shown to cause emotional instability, irritability, and depression
  • A study found significantly higher levels of copper and copper:zinc ratio, as well as lower levels of zinc, among those diagnosed with anxiety
  • 8 weeks of zinc and vitamin B-6 therapy was given to 20 of the 38 anxiety patients; post-treatment levels of zinc were found to normalize, leading to a decrease in the copper:zinc ratio as well as a significant improvement in anxiety symptoms

Anxiety disorders are the most common class of all psychiatric, affecting roughly 1/3 of the US population and about 1/8 of the worldwide population. Anxiety symptoms can include irritability and anger, depression, the lack of ability to focus or concentrate, racing thoughts, trouble sleeping, light sensitivity, migraines, OCD or obsessive behavior, intrusive thoughts, restlessness, disorganization, and panic attacks.

Studies have shown a relationship between magnesium and anxiety and depression as well as omega-3 fatty acids; zinc and copper are two other essential nutrients that may play a role.

How could zinc affect anxiety?

Zinc has been labeled as one of the most important trace elements in the body, and is an essential nutrient necessary for the proper function of many physiological processes, including neurological functioning. Previous studies have found an increased incidence of zinc deficiency among individuals with anxiety and depression. Zinc has protective effects against DNA damage and oxidative stress, which have also been correlated with anxiety. Prolonged deficiency of zinc has been shown to cause emotional instability, irritability, and depression.

Correlations between anxiety and levels of zinc, copper, and the copper:zinc ratio

A study by A.J. Russo, published in Nutrition and Metabolic Insights, looked at the relationship of zinc and copper to anxiety symptoms. In this study, serum levels of zinc, copper, and copper:zinc ratio were measured in a group of 38 females diagnosed with anxiety and compared to a group of 16 female controls, both pre-treatment and post-treatment. The severity of anxiety symptoms was also tracked.

Significantly higher levels of copper and copper:zinc ratio, as well as lower levels of zinc, were found in those with anxiety.

Click to Enlarge & Print

A minimum of 8 weeks of zinc and vitamin B-6 therapy was given to 20 of the 38 anxiety patients. While copper levels did not decrease significantly, post-treatment levels of zinc were found to normalize, leading to a decrease in the copper:zinc ratio as well as a significant improvement in anxiety symptoms.

The chart above shows the change in anxiety symptom rating and serum zinc levels for those participants diagnosed with anxiety who were given 8 weeks of zinc and vitamin B6 supplementation. As can be seen, from pre-treatment to post-treatment measurements, anxiety symptom ratings decreased by 31% (p=0.0133) while zinc serum levels increased by 25% (p=0.0004).

Could your zinc and copper levels be contributing to anxiety?

Are you struggling with anxiety symptoms? Do you know your magnesium, zinc, copper, and copper:zinc ratio levels? Make sure you know the status of these important elements and others by adding the Magnesium Plus Elements blood spot test to your vitamin D kit, and see if changes in your diet and supplementation could improve your element status and health outcomes.

Make Sure You Are Getting Enough of these Essential Nutrients!

Having and maintaining healthy vitamin D levels and other nutrient levels can help improve your health now and for your future. Choose which additional nutrients to measure, such as your omega-3s and essential minerals including magnesium and zinc, by creating your custom home test kit today. Take steps to improve the status of each of these measurements to benefit your overall health. With measurement you can then determine how much is needed and steps to achieve your goals.  You can also track your own intakes, symptoms and results to see what works best for YOU.

Enroll in D*action and Test Your Levels Today!

What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?

Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.

STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.

STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).

STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.

STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.

STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.

STEP 6 – Adjust, Repeat…

Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.

NEWS ALERT

The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.

These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.

Review the Latest Nutrient Research for COVID-19

GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:

  • Vitamin D
  • Omega-3 Index
  • Essential elements magnesium, selenium, and zinc
  • hsCRP

Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!

Please let us know if you're interested in helping sponsor this project.

CLICK HERE for updates and new information about the project.

Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

Click Here to Access the Test Page

How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called

For each specific supplement, you can track what days you take it, how much, and many other details.  This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!